Treatment of Advanced Thymoma and Thymic Carcinoma

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Thymoma and thymic carcinoma.

Thymic tumors comprise a heterogeneous group of neoplasms with a wide spectrum of clinical presentations. The evolution of the disease is often unpredictable, ranging from an indolent attitude to the possibility of intra- and extrathoracic spread. From the histological point of view, thymoma and thymic carcinoma are the most frequent subtypes and arise only from thymic epithelial cells. Other h...

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Novel Treatments for Thymoma and Thymic Carcinoma

The rarity of thymic epithelial tumors (TETs) creates unique challenges in conducting translational research and developing newer paradigms of treatment (1). Nevertheless, steady progress in genome research, the development of thymic cell lines, and an increase in collaborative efforts between various institutions have helped in fostering an increase in the understanding of the biology of TETs ...

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Thymoma and thymic germinal center.

A previous study of 70 cases of thymoma described in 1966 by the author1 reported that definite germinal centers were found in the normal thymic tissue attached to one case of thymoma associated with myasthenia gravis, and that this was very interesting from the point of view of whether thymoma or thymic germinal center was a more important occurrence of a myasthenic condition. Since then routi...

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Predictors of survival in patients with locally advanced thymoma and thymic carcinoma (Masaoka stages III and IVa).

OBJECTIVE We sought to evaluate factors influencing long-term survival of patients with locally advanced thymoma/thymic carcinoma (Masaoka stages III and IVa) treated by immediate surgery or induction therapy plus surgery. METHODS From January 1991 to April 2007, we surgically treated 61 patients with locally advanced thymoma/thymic carcinoma (Masaoka stages III and IVa). Staging included tot...

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ژورنال

عنوان ژورنال: Current Treatment Options in Oncology

سال: 2008

ISSN: 1527-2729,1534-6277

DOI: 10.1007/s11864-009-0083-7